Additional ingredients: dimethyl sulfoxide, ethanol, polyethylene glycol, propylene glycol.

TARGET ANIMALS:

Cats, dogs.

INDICATIONS:

OTOFLOX is indicated for the treatment of small non-productive animals (dogs, cats and decorative rabbits) with otitis of different etiologies, including those caused by ectoparasites and/or complicated by bacterial or fungal infections.

ROUTES OF ADMINISTRATION AND DOSAGES:

Ear medications are applied after cleaning of animal’s ears and ear canals. The aim of cleaning is to remove earwax, exudates and scabs. Then the product is instilled twice daily in each ear, at a dosage as shown in Table 1, for 5-10 consecutive days depending on the clinical manifestations.

Dosage:

Excipients: propylene glycol, methylparaben, propylparaben, purified water.

ADMINISTRATION:

PHYTOCAT is administered for the prevention and treatment of cats and dogs with the urological syndrome, urolithiasis, and inflammatory diseases of kidneys, bladder, and urinary tract (pyelitis, cystitis,
and urethritis

ROUTE OF ADMINISTRATION AND DOSAGES:

For the treatment of urological syndrome, the early stages of urolithiasis, inflammatory diseases of kidneys, bladder, and urinary tract, the drug is used in combination with symptomatic agents, orally,twice daily for 3 weeks at following doses:

RELAX is administered to animals in the following cases: for short anesthesia with short-term (up to 5 minutes)surgical and diagnostic procedures–once, for introductory anesthesia and maintenance of basic anesthesia by additional injections, for introductory anesthesia at inhalation anesthesia.

Anesthesia induction:

COMPOSITION

100 ml of the drug contains active ingredients:

Florfenicol – 2.5 g;

Prednisolone acetate – 0.1 g.

Excipients: methylpyrrolidone, polyvinylpyrrolidone, ethyl alcohol, isopropyl alcohol, propylene glycol, glycerin, dimethyl sulfoxide.

PHARMACEUTICAL FORM

Transparent liquid, colorless or light yellow color.

PHARMACOLOGICAL PROPERTIES

ATC VET CODE QD06A – TOPICAL ANTIBIOTICS.

Florfenicol is a thiamphenicol derivative in which the hydroxyl group is replaced by a fluorine atom, which provides its antibacterial activity against acetyltransferase-synthesizing bacteria.

Florfenicol is effective as bacteriostatic against gram-positive (Streptococcus spp., Staphylococcus spp.) and gram-negative bacteria (Fusobacterium necrophorum, Bacteroides melaninogenicus, Pasteurella spp., Salmonella spp., Proteus spp., Pseudomonas spp., Haemophilus spp.), as well as against Mycoplasma spp., Rickettsia spp., Chlamydia spp.

Florfenicol inhibits protein synthesis in bacterial cells. In the protoplasm, it binds to the 70S-subunits of ribosomes, inhibits the enzymatic activity of peptidyl transferase, thus inhibiting the synthesis of proteins in the ribosomes of the corresponding bacteria.

When used externally, Florfenicol acts locally and almost does not penetrate into the circulatory system. In animals’ bodies, it is metabolized to form the florfenicol amine metabolite. Florfenicol and its metabolites are excreted mainly in the urine, and less in the feces.

Prednisolone is a synthetic glucocorticoid. It has anti-inflammatory, anti-allergic, and anti-exudative effects. The anti-inflammatory effect is due to the inhibition of the metabolism of arachidonic acid and the release of inflammatory mediators.

When applied topically, Prednisolone is absorbed, and released into the bloodstream. 90% of Prednisolone in plasma is bound (with transcortin and albumin). It biotransforms by oxidation, predominantly in the liver; oxidized forms undergo glucuronidation and sulfatization. It is excreted in the urine and feces in the form of metabolites, and partially as unchanged.

ADMINISTRATION

Treatment of dogs, cats and rabbits of decorative breeds with dermatitis, panaritium, pyoderma, eczema, as well as with wounds (including after castration), with scratching, bites, bruises, ulcers caused by pathogens susceptible to Florfenicol.

DOSAGE

Before using the drug, the affected area is thoroughly cleaned of exudates, necrotic tissues.

First, shake the bottle and, holding it at a distance of 5-10 cm from the surface of the damaged skin area, press the sprayer 1-2 times and treat the area approx. 5×5 cm.

It is recommended to apply the drug every 12 hours until complete healing.

The duration of treatment depends on the extent of the lesion and the rate of healing.

CONTRAINDICATIONS

Do not administer to animals with hypersensitivity to the drug components.

Do not use concomitantly with thiamphenicol or chloramphenicol.

SIDEEFFECTS

Allergic reactions are possible with individual hypersensitivity to the components of the drug.

PRECAUTIONS

Do not allow the drug to get into the eyes of animals and humans. Do not allow the animal to lick the drug for 5 minutes. Shake the bottle with the drug before use.

Treatment of animals with the drug should be carried out as far as possible from open flames and heating devices.

PACKAGE

Bottles made of polymeric materials with a spray of 9, 30; 50; 100; 200; 250; 500 ml.

SHELF LIFE

2 years.

Expiration date after first use: before the expiration date.

STORAGE CONDITIONS

Dark place, out of the reach of children, between 5°С to 25° С.

FOR VETERINARY USE ONLY!

COMPOSITION

1 ml of the drug contains active ingredients:
Butafosfan – 100 mg; Cyanocobalamin – 0.05 mg; Nicotinamide – 5 mg;
L-carnitine hydrochloride – 20 mg.

Excipients.

Pharmacological properties

L-cyn is a complex drug, the action of which is due to the properties of the active ingredients: butafosfan, a complex of B vitamins (vitamin B12, vitamin B3(PP)) and the vitamin-like substance of B-group (L-carnitine). The drug has tonic properties, normalizes metabolic and regenerative processes, has a stimulating effect on protein, carbohydrate and fat metabolism, increases the body’s resistance to the effects of adverse environmental factors, infections and toxins, and promotes the growth and development of animals, including birds.

Butafosfanis an organic phosphorus compound that affects a number of the assimilation processes in animals’ body, stimulates protein synthesis, accelerates the growth and development of animals, normalizes liver functioning, increases the nonspecific resistance of the body; it promotes bone tissue formation. In stressful situations butafosfan normalizes the level of the stress hormone –hydrocortisone – thereby improving the utilization of glucose in the blood and helping to preserve the body’s energy resources. Butafosfan does not accumulate in the body and does not cause adverse effects typical to stimulants and inorganic phosphorus.

Cyanocobalamin (vitamin B12) as a metabolite, activates the metabolism of carbohydrates, proteins,and lipids, promotes the synthesis of labile groups in the formation of choline, methionine, nucleic
acids, creatine; accumulation of compounds with sulfhydryl groups in erythrocytes. As a growth factor, it stimulates bone marrow function, which is necessary for normoblastic erythropoiesis.Cyanocobalamin normalizes the functioning of the liver and nervous system, activates the blood coagulation system, and in high doses causes an increase in thromboplastic activity and prothrombin activity. Vitamin B12is necessary for the formation of red blood cells in the bone marrow. In the
body, it binds to proteins by 90%. It is excreted through the kidneys and with bile. It penetrates through the placental barrier.

Nicotinamide(Vitamin B3(PP)) stimulates the production of nicotinamide adenine dinucleotide phosphate (NADPH) and nicotinamide adenine dinucleotide (NAD), which regulate the course of
most redox reactions, ensuring the normalization of many types of metabolism (including energy).It takes part in the metabolism of fats, proteins, amino acids, purines, tissue respiration, glycogenolysis. Nicotinamide contributes to the body’s resistance to infectious diseases, has detoxification properties, it is rapidly distributed in the tissues and passes through the placental barrier. It is metabolized in the liver to form N-methyl-nicotinamide, methyl-pyridone-carboxamides, glucuronide and a complex with glycine. It is excreted through the kidneys with urine.

L-carnitine is a substance of natural origin, belonging to the complex of B vitamins (the so-called vitamin B11), a product of the biosynthesis of lysine and methionine. It performs several important functions in the body, including: detoxification, stimulation of metabolic processes, strengthening of blood vessels, and stimulation of tissue regeneration.

Its use leads to an increase in body endurance, an improvement in heart function, an increase in muscle mass due to the acceleration of metabolic processes in cells, an improvement in the penetration of vitamins and minerals into cells, and the removal of decay products and and reducing the risk of fatty liver disease.

Administration

For the treatment of calves, lambs, kids, dogs, fur animals with iron deficiency anaemia and for the prevention of disease, in case of haemorrhage and haemorrhagic diathesis.

Dosages

The drug is administered to animals intramuscularly, subcutaneously or intravenously (slowly) once a day for 4-5 days in doses:

COMPOSITION

1 g of the drug contains following active substances:

Ciprofloxacin (as ciprofloxacin hydrochloride) – 100.0 mg;
Colistin sulfate – 1 000 000 IU;

Excipients.

Pharmacological properties

CIPROCOLIN is a complex drug, its therapeutic effect is due to the synergistic effects of the active components of the drug – ciprofloxacin and colistin sulfate.
Ciprofloxacin belongs to the group of fluoroquinolones.
Colistin is an antibiotic of the polymyxin group, which is synthesized by the aerobic spore-forming Bacillus polymyxa. The drug has a bactericidal effect against Gram-negative bacteria.

Administration

The drug is used for therapeutic purposes in dogs and cats with acute and chronic bacterial infections, caused by pathogens susceptible to Ciprofloxacin and Colistin (infections of the digestive tract, respiratory organs, biliary tract, genitourinary system; of the skin, and soft tissues, of eyes and ears, bones and joints); and in secondary infections on the background of viral diseases.

Routes of administration and dosages

Before using the drug, prepare a solution from the powder. To do this, pour 100 ml of drinking water at room temperature into a bottle with powder (up to the mark) and shake vigorously until the powder is completely dissolved.
Draw up the required amount of the resulting solution with a dosing syringe.
The resulting solution is administered orally to dogs and cats orally in doses: 1 ml per 1 kg of animal body weight 1 time per day. The course of treatment is 3-5 days.
Shake the vial vigorously before each subsequent use.

Shelf life

36 months

Storage conditions

Store in a dark place, out of the reach of children at 5° to 25°С. Shelf life after dilution is 7 days.

COMPOSITION

1 ml of the drug contains following active substances:

Amoxicillin (as Amoxicillin trihydrate) – 150.0 mg;

betamethasone (as betamethasone dipropionate) – 0.5 mg;

Excipients.

Pharmacological properties

SPECTRAN is a complex drug with a pronounced antimicrobial and anti-inflammatory effect. The active ingredients of Spectran are the antibiotic amoxicillin and the corticosteroid batamethasone; amoxicillin has a wide spectrum of antimicrobial action, batamethasone enhances anti-inflammatory processes in the body, and prevents the occurrence of possible allergic reactions (including those to the components of the drug).

Administration

Treatment of cattle, and pigs in case of respiratory diseases (bronchitis, pneumonia, rhinitis) caused by pathogens susceptible to Amoxicillin.

Routes of administration and dosages

Intramuscularly or subcutaneously once at a dose of 1 ml per 10 kg body weight. If necessary, the product is administered again in 48 hours.

Withdrawal period

For meat: 21 days after last treatment, for milk: 3 days after last treatment.

Shelf life

24 months. After first vial opening: 28 days if stored in dark place at 5° to 25°С.

Storage conditions

Store in dark place, out of the reach of children at5° to 25°С.

INDICATIONS:

Gastroenteril ® oral suspension is indicated for the treatment of associated diarrhea to giardias, in dogs and cats. It is also indicated in enteric infections andsystemic diseases caused by obligate anaerobic bacteria sensitive to Metronidazole.

ROUTE OF ADMINISTRATIONAND DOSE:

Orally.

DOSAGE:

1 mL / Kg of weight, twice a day for 5 to 7 days..
* In the case of systemic anaerobic infections, therapy can be prolonged for 6weeks.
Shake vigorously before using.

PRESENTATION:

120 mL bottle

PRODUCED BY LaboratoryDrag Pharma Chile Invetec S.A.

COMPOSITION

Each mL of the product contains:
Doxycycline Hyclate………………..11.08 mg
(Equivalent to 10 mg of Doxycycline basic)
Excipients q.s.p………………………….1 mL

INDICATIONS

Doximicin® is indicated for the treatment of upper and lower respiratory tract infections caused by sensitive etiological agents, such as primary infectious pictures or those associated with respiratory virosis, bacterial skin infections, eye and peri-eye infections caused by Chlamydiae or other strains Sensitive, Canine Ehrlichiosis and Canine and Feline Mycoplasmosis (Hemobartonellosis).

Presentation in oral solution, in addition to facilitating administration, avoids the risk of causing esophageal narrowing in cats.

ROUTE OD ADMINISTRATION AND DOSAGE

Oral route.

Dogs and cats: 10 mg/Kg, once a day for 14 to 21 days.
Product dose: 1 mL per Kg of weight, once a day for 14 to 21 days. In respiratory tract infections, administer it for a maximum of 10 days.

CONTRAINDICATIONS

Do not use Doximicin® in animals hypersensitive to Doxycycline.

PRECAUTIONS

Use caution when administered to young animals.

WARNINGS

Keep out of reach of children.

CONSERVATION

Store in a dry place, at room temperature between 15° and 30°C and protected from sunlight.

CONDITION OF SALE

Supply only on veterinary prescription.

PRESENTATION

In a bottle with 60 ml. Includes dosing syringe and dropper.

PREPARED BY

Drag Pharma Laboratory.

RECORDS

Reg. SAG No 2029-B

COMPOSITION

Each 100 mL of suspension contains:
Beta-(1,3/1,6)-D-glucans……………. 1.0 g
Excipients q.s.p………………………100 mL

ROUTE OD ADMINISTRATION AND DOSAGE

Oral administration. Betaglucans can be added to the food or administered directly to the oral cavity.

Recommended dose:

Dogs and cats:
Administer 2 mL for every 1 to 5 Kg of body weight, once a day for 2 to 3 months, or as needed.

WARNINGS

Mantener fuera del alcance de los niños.

OBSERVATIONS

• Shake vigorously before use.
• It does not constitute a complete food.
• Exclusive use in animal feed

CONSERVATION

Store in a cool, dry place and away from light, at no more than 30ºC

CONDITION OF SALE

Over the counter.

PRESENTATION

Bottle with 60 mL

PREPARED BY

Laboratorio Drag Pharma Chile Invetec S.A.

RECORDS

Reg. LENAA N°: RM 03-008N